Intervention: Nutrafol Women (n = 50), Nutrafol Women's Balance (n = 50), Nutrafol Women's Vegan (n = 50), Nutrafol Postpartum (n = 50) or Nutrafol Men (n = 50). Participants took 4 capsules daily for 180 days.
Methods: Subjects visited the clinic for evaluation at baseline, Day 90 and Day 180. Hair shaft diameter was assessed using light microscopy. Hair breakage/shedding was assessed via a four-region hair pull test. Hair qualities were assessed by dermatologist evaluation using a 5-point scale. Participants also completed a self-perception questionnaire and asked whether they agreed with statements such as 'My hair is less dry/brittle' and 'My hair quality improved'.
Study Duration: 180 days
Eligibility Criteria:
- Nutrafol Women: Healthy female subjects aged 18 - 44.
- Nutrafol Women's Balance: Healthy perimenopausal, menopausal and postmenopausal women aged 45 - 70.
- Nutrafol Women's Vegan: Healthy plant-based female subjects aged 18 - 44.
- Nutrafol Postpartum: Parous female subjects aged 18 - 44.
- Nutrafol Men: Healthy male subjects aged 25 - 50.
All subjects had thinning hair, confirmed by the study dermatologist.
For more, plus the exclusion criteria, see:
Key Findings
1
Hair fiber diameter was significantly increased after 180 days of supplementation with all Nutrafol formulations (P<0.05 for all formulations, relative to baseline). Subjects in the Nutrafol Women group increased by 8%, Nutrafol Women’s Vegan by 9%, Nutrafol Balance by 8%, Nutrafol Postpartum by 6% and Nutrafol Men by 7% . These outcomes suggest that the Nutrafol formulations enhanced thickness and strength.
Changes in hair fiber diameter following supplementation with Nutrafol formulations. *P<0.05 compared to baseline. Adapted from Draelos et al., A Six-Month Open-Label Prospective Clinical Study to Evaluate Improvements in Hair Strength and Growth in Men and Women using Standardized Nutraceuticals. European Academy of Dermatology and Venereology (2025), September 17 – 20.
2
The hair pull test revealed a reduction in the total number of hairs removed after 180 days of supplementation with all Nutrafol formulations, with statistical significance reached for Nutrafol Women (P<0.005), Nutrafol Women’s Vegan (P<0.005) and Nutrafol Women’s Balance (P<0.001). In addition, all groups also exhibited reductions in broken hairs, which reached statistical significance for Nutrafol Women (P=0.038) and Nutrafol Women’s Balance (P<0.001).
3
Average investigator ratings were significantly improved across parameters including hair strength, length and growth (P<0.01 for all parameters, relative to baseline).
Heat maps showing average investigator ratings over the course of the study for each parameter. Adapted from Draelos et al., A Six-Month Open-Label Prospective Clinical Study to Evaluate Improvements in Hair Strength and Growth in Men and Women using Standardized Nutraceuticals. European Academy of Dermatology and Venereology (2025), September 17 – 20.
Results from the self-perception questionnaire revealed that a significant proportion of subjects in each group agreed with the question.
Outcomes from the participant self-perception questionnaire.
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THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE.
This information is provided as a medical and scientific educational resource for the use of dieticians and other licensed healthcare professionals. This information is intended for Practitioners to use as the basis for determining whether to recommend these products to their clients. All recommendations regarding protocols, dosing, prescribing and/or use instructions should be tailored to the individual needs of the client considering their medical history and concomitant therapies. This Information is not intended for use by consumers.
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