Intervention: Sugar-Sweetened ORS (SS-ORS, Liquid I.V. Hydration Multiplier), Sugar-Free Allulose-Sweetened ORS (SF-ORS, Liquid I.V. Sugar Free (with allulose)), Sugar-Free Allulose-Sweetened ORS (SF-ORS*, Liquid I.V. Sugar Free (with amino acids)), or water. All participants (n = 28) completed the three active arms and the water arm of the protocol in a crossover study design. Each day, participants consumed 1L of the four beverages and urine was collected at the end of hours 1-4 post-intake.
Study Duration: 4 hours
Eligibility Criteria:
1. Healthy male and female participants, aged 18 - 45 years.
2. Consumes 2 L/day (female) or 2.5 L/day (male) water prior to study.
3. Able to fast for ~15 hours prior to each visit.
For more, plus the exclusion criteria, see
At the 240-minute (4-hour) timepoint, water exhibited significantly greater cumulative urine mass when compared to SS-ORS (P = 0.004), SF-ORS (P < 0.0001) and SF-ORS (P < 0.0001).
Similar findings were noted for net fluid balance, with all Liquid I.V. formulations significantly outperforming water at the 240-minute (4-hour) timepoint: SS-ORS (P = 0.004); SF-ORS (P < 0.0001); and SF-ORS (P < 0.0001).
For the Beverage Hydration Index, all Liquid I.V. formulations significantly outperformed water at the 240-minute (4-hour) timepoint: SS-ORS (P = 0.028); SF-ORS (P = 0.02); and SF-ORS (P = 0.001).
This information is provided as a medical and scientific educational resource for the use of dieticians and other licensed healthcare professionals. This information is intended for Practitioners to use as the basis for determining whether to recommend these products to their clients. All recommendations regarding protocols, dosing, prescribing and/or use instructions should be tailored to the individual needs of the client considering their medical history and concomitant therapies. This Information is not intended for use by consumers.
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