Intervention: Observational comparison of women following a vegan diet (n = 33) versus non-vegan diet (n = 32) for ≥1 year (self-reported); no dietary intervention was administered.
Study Duration: Observational study ≥1 year
Eligibility Criteria:
Vegan participants exhibited measures consistent with healthier metabolic outcomes: this included reduced BMI (P < 0.05 relative to non-vegans) and lower systolic and diastolic blood pressure (P < 0.05 for both relative to non-vegans).
Scores for fine lines and wrinkles exhibited a significant interaction with diet and age (p<0.05), where vegan participants had improved scores beginning in their late twenties compared to non-vegans.
Women following a vegan diet included more fruits and vegetables (78% vs. 34% consuming once or more/day) and legumes and grains (61% vs. 28%, consuming 4-6 times/week) compared to women following a non-vegan diet.
While the methylation differences in skin cells were not significant, vegan participants consistently showed higher methylation levels at specific sites and regions, regardless of age or where the samples were taken
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